Derek Wolfe hurt during practice

Denver Broncos defensive end Derek Wolfe has left a joint practice with the San Francisco 49ers because of a left ankle injury.

Wolfe was injured Wednesday while pass rushing during 11-on-11 scrimmaging against the 49ers’ first-team offense. He limped to the locker room, leaning on team trainers walking on either side of him.

Coach Gary Kubiak said after practice that Wolfe rolled his ankle. There was no immediate word on the severity of the injury.

On Monday, the Broncos lost starting defensive end Vance Walker to a season-ending knee injury. Walker tore his right ACL during drills when he became entangled with a pass blocker.